S1PC™

We aim to unlock the full value of S1PC
and deliver its benefits widely to
support healthier futures for people
everywhere

S1PC is a trademark of Wakunaga Holdings Co., Ltd.

Overview

A naturally derived amino acid.
It is known to be generated during the long term aging process of fresh garlic, and extensive research has reported a variety of functions that support the maintenance and promotion of health.

Detail

S1PC structural formula

S1PC content of each garlic^{※Internal data}

Raw garlic	Black garlic	Aged garlic extract
N.D	0~0.05mg/g	2~4mg/g

TOPICS

News 2026.05: New Findings in Anti-Aging Research on S1PC Published in Cell Metabolism (May 8 (JST))

News 2026.05: Official YouTube Channel “WAKUNAGA Channel” Now Live

News 2026.05: S1PC Website Release Announcement

Publications

S1PC 2026.05: Jun-ichiro S et al. Garlic-derived metabolite activates LKB1, promotes adipose eNAMPT secretion, and improves age-related muscle function via hypothalamic signaling. Cell Metab. Online ahead of print.

S1PC 2025.03: Nakamoto M, Kunimura K, Ohtani M. Pharmacokinetics of sulfur-containing compounds in aged garlic extract: S-Allylcysteine, S-1-propenylcysteine, S-methylcysteine, S-allylmercaptocysteine, and others (Review). Exp Ther Med. 2025 Mar 26;29(5):102.

S1PC 2024.09: Kunimura K, Nakamoto M, Ushijima M. S-1-Propenylcysteine enhances endurance capacity of mice by stimulating fatty acid metabolism via muscle isoform of carnitine. J Nutr. 2024 Sep;154(9):2707-2716.

Contact us

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